DETAILED NOTES ON ACTIVE INGREDIENT IN KETAMINE

Ketamine makes solid analgesia in neuropathic pain states, presumably by inhibition from the NMDAR [8,23]. The NMDAR can be an excitatory glutamatergic receptor existing at spinal and supraspinal web sites and involved with the afferent transmission of nociceptive alerts. In chronic pain states prolonged nociceptive stimulation causes activation an